Notice of retraction
Vol. 32, No. 8(2), S&M2292

Print: ISSN 0914-4935
Online: ISSN 2435-0869
Sensors and Materials
is an international peer-reviewed open access journal to provide a forum for researchers working in multidisciplinary fields of sensing technology.
Sensors and Materials
is covered by Science Citation Index Expanded (Clarivate Analytics), Scopus (Elsevier), and other databases.

Instructions to authors
English    日本語

Instructions for manuscript preparation
English    日本語

Template
English

Publisher
 MYU K.K.
 Sensors and Materials
 1-23-3-303 Sendagi,
 Bunkyo-ku, Tokyo 113-0022, Japan
 Tel: 81-3-3827-8549
 Fax: 81-3-3827-8547

MYU Research, a scientific publisher, seeks a native English-speaking proofreader with a scientific background. B.Sc. or higher degree is desirable. In-office position; work hours negotiable. Call 03-3827-8549 for further information.


MYU Research

(proofreading and recording)


MYU K.K.
(translation service)


The Art of Writing Scientific Papers

(How to write scientific papers)
(Japanese Only)

Sensors and Materials, Volume 33, Number 1(2) (2021)
Copyright(C) MYU K.K.
pp. 233-240
S&M2449 Research Paper of Special Issue
https://doi.org/10.18494/SAM.2021.3074
Published in advance: December 23, 2020
Published: January 22, 2021

Pattern-recognition-based Identification of Proteases and Their Complexes by a One-component Array Composed of a Dansyl-modified Charged Polymer [PDF]

Shunsuke Tomita and Ryoji Kurita

(Received October 22, 2020; Accepted December 14, 2020)

Keywords: proteases, biosensors, multivariate analysis, polymers

Pattern-recognition-based protein sensing has recently attracted attention as an alternative to conventional specificity-based sensing. Herein, we present a simple one-component array consisting of a charged poly-L-lysine modified with environment-responsive dansyl fluorophores (PLL-Dnc) for the identification of proteases. An array of PLL-Dnc dissolved in three buffer solutions with different pH values is capable of producing fluorescent patterns that are unique to each protease via diverse interactions, allowing the identification of eight proteases by multivariate analysis. Although it is impractical to quantify mixed samples of proteases and their inhibitor proteins by conventional enzyme-activity-based assays, the present array has enabled the discrimination of mixtures of trypsin and α1-antitrypsin (ATT) with different compositions. Considering that the PLL-Dnc array has high accessibility and consists of only a single polymeric material that can be easily prepared, our method is expected to allow screening for the formation of protein-protein complexes, as well as the detection of disease-associated proteases.

Corresponding author: Shunsuke Tomita and Ryoji Kurita


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Cite this article
Shunsuke Tomita and Ryoji Kurita, Pattern-recognition-based Identification of Proteases and Their Complexes by a One-component Array Composed of a Dansyl-modified Charged Polymer, Sens. Mater., Vol. 33, No. 1, 2021, p. 233-240.



Forthcoming Regular Issues


Forthcoming Special Issues

Special Issue on Micro-nano Biomedical Sensors, Devices, and Materials
Guest editor, Tetsuji Dohi (Chuo University) and Seiichi Takamatsu (The University of Tokyo)


Special Issue on Artificial Intelligence in Sensing Technologies and Systems
Guest editor, Prof. Lin Lin (Dalian University of Technology)


Special issue on Novel Materials and Sensing Technologies on Electronic and Mechanical Devices Part 3
Guest editor, Teen-Hang Meen (National Formosa University), Wenbing Zhao (Cleveland State University), and Hsien-Wei Tseng (Yango University)


7th Special Issue on the Workshop of Next-generation Front-edge Optical Science Research
Guest editor, Takayuki Yanagida (Nara Institute of Science and Technology)


Special Issue on Sensing and Data Analysis Technologies for Living Environment, Health Care, Production Management and Engineering/Science Education Applications (Selected Papers from ICSEVEN 2020)
Guest editor, Chien-Jung Huang (National University of Kaohsiung), Rey-Chue Hwang (I-Shou University), Ja-Hao Chen (Feng Chia University), Ba-Son Nguyen (Research Center for Applied Sciences)
Call for paper


Special Issue on Materials, Devices, Circuits, and Analytical Methods for Various Sensors (Selected Papers from ICSEVEN 2020)
Guest editor, Chien-Jung Huang (National University of Kaohsiung), Ja-Hao Chen (Feng Chia University), and Yu-Ju Lin (Tunghai University)
Conference website
Call for paper


Copyright(C) MYU K.K. All Rights Reserved.