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Vol. 34, No. 8(3), S&M3042

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Vol. 32, No. 8(2), S&M2292

Print: ISSN 0914-4935
Online: ISSN 2435-0869
Sensors and Materials
is an international peer-reviewed open access journal to provide a forum for researchers working in multidisciplinary fields of sensing technology.
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Sensors and Materials, Volume 16, Number 6 (2004)
Copyright(C) MYU K.K.
pp. 301-307
S&M567 Research Paper in Biosensors and Related Areas
Published: 2004

Bitterness-Masking Effect of Phospholipids on Lipid/Polymer Membranes [PDF]

Hidenori Shimakawa, Masaaki Habara and Kiyoshi Toko

(Received February 24, 2004; Accepted August 26, 2004)

Keywords: taste sensor, lipid/polymer membrane, bitterness, masking effect, atomic force microscope

Phospholipids such as phosphatidic acid exert a bitterness-masking effect without changing other taste qualities. In a previous study, we detected and qualified this suppression of bitterness using a taste sensor whose transducer was composed of several kinds of lipid/polymer membranes with different characteristics. The response to quinine hydrochloride decreased with increasing phospholipid concentration in a manner similar to human gustatory sensation. In this study, we observed the structural changes of a membrane surface using an atomic force microscope (AFM) and detected the adsorption of quinine hydrochloride and the masking effect of phospholipids. As a result of AFM measurements, we confirmed that the the masking effect was caused by blocking the adsorption of bitter substances onto to the membrane.

Corresponding author: Kiyoshi Toko


Cite this article
Hidenori Shimakawa, Masaaki Habara and Kiyoshi Toko, Bitterness-Masking Effect of Phospholipids on Lipid/Polymer Membranes, Sens. Mater., Vol. 16, No. 6, 2004, p. 301-307.



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